Ledig stilling på Universitetet i Oslo

Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Research technician - Computational Biology & Gene Regulation group

Deadline: 08.10.2021

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.


Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Description

A 2-year funded lab technician position is available in the Computational Biology & Gene Regulation group led by Anthony Mathelier at the Centre for Molecular Medicine Norway (NCMM), University of Oslo, Nordic EMBL partner for Molecular Medicine (see this link for further information). The position is part of the recently funded project “Cis-regulatory signatures for improved identification and stratification of breast cancer subtypes” selected through the Rosa sløyfe 2020 - Personalized breast cancer treatment call by the Norwegian Cancer Society (Kreftforeningen). The position will start as early as possible and is funded for two (2) years.

The project aims at providing a map of active regulatory regions in breast cancer patients and developing machine-learning approaches to better stratify patients and identify breast cancer subtype cis-regulatory signatures. The selected candidate will specifically be involved in the experimental work, primarily the implementation and application to cell lines and patient material of the Super-Low Input Carrier Cap Analyses of Gene Expression (SLIC-CAGE) protocol (Cvetesic et al., Genome Research, 2018). Lab work will be performed with a senior researcher in the group (Dr. Roza Berhanu Lemma) with co-supervision between our group and our collaborators Drs. Xavier Tekpli and Vessela Kristensen (Oslo University Hospital).

We seek a highly motivated individual with documented lab experience with library preparation, the generation of high-throughput genomics data, eukaryotic cell culture, and routine molecular biology techniques. We are looking for applicants excited about being immersed in a scientific environment combining life sciences and computer science to study gene expression regulation. The successful candidate will be collaborative, independent, with strong enthusiasm for research. Being familiar with gene expression regulation in general and CAGE is an advantage. The position is open to applicants with a Master degree in molecular biology, life sciences, or related fields or with equivalent experience. We offer a stimulating environment with excellent working and social benefits.

Requirements

  • Master degree in molecular biology, life sciences, or related fields or with equivalent experience
  • Documented experience in routine molecular biological techniques
    • cell culture
    • PCR
    • qPCR
    • RNA isolation
    • buffer preparation, various reagents, and chemical handlings
  • Documented lab experience with library preparation and the generation of high-throughput genomics data
  • Ability to collaborate with researchers from different fields and at different career stages
  • Willingness to be part of a team to share knowledge and skills
  • High drive for science
  • Proficiency in English

Advantageous skills

  • Knowledge of CAGE
  • Knowledge of eukaryotic gene expression regulation
  • Ability to communicate science
  • Day to day lab management skills
  • Experience with analysis of genomics data sets

How to apply

Applicants should include (1) a cover letter outlining motivations, career goals, and past achievements, (2) a CV, and (3) two to three referees contact information. These should be provided in English and should be uploaded as a single PDF document.

The application with attachments must be delivered in our electronic recruiting system.

We offer

  • The candidate position will be placed as SKO 1020 (position code) with salary NOK 468 300 - 543 500 per year depending on qualifications.
  • The University of Oslo has an agreement for all employees, aiming to secure rights to research results and intellectual property.
  • attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

Formal regulations

Interviews with the best qualified candidates will be arranged.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a

balanced gender composition. We also want to have employees with diverse expertise, combinations of subjects, life experience and perspectives. We will make adjustments for employees who require this.

If there are qualified applicants with special needs, gaps in their CVs or immigrant backgrounds, we will invite at least one applicant in each of these groups to an interview.

Contact information

Inquiries about the position can be directed to Anthony Mathelier at [email protected].

About the application: Nina Modahl ([email protected]).

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