LEDIG STILLING VED UIT NORGES ARKTISKE UNIVERSITET

Postdoctoral Research Fellow in Haematopoietic Stem Cell Research

Deadline: 09.12.2021

UiT The Arctic University of Norway

UiT – Developing the High North

UiT The Arctic University of Norway is a multi-campus research university and the northernmost university of the world. Our central location in the High North, our broad and diverse research and study portfolio, and our interdisciplinary qualities make us uniquely suited to meet the challenges of the future. At UiT you can explore global issues from a close-up perspective.

Credibility, academic freedom, closeness, creativity and commitment shall be hallmarks of the relationship between our employees, between our employees and our students and between UiT and our partners.


The Faculty of Health Sciences

The Faculty of Health Sciences represents a newly created entity gathering almost all possible health study programs. This facilitates an unique interdisciplinarity and innovation in health education and research. We work closely with the services in the North to solve tomorrow's challenges.

Faculty of Health Sciences / Department of Medical Biology

The position

A Postdoctoral Research Fellow position is available at the Department of Medical Biology (IMB), Faculty of Health Sciences in Haematopoietic Stem Cell Research. The position is affiliated with the research group Stem Cells, Ageing and Cancer (SAC).

The position is a fixed term position for a duration of three years. Appointment to the position of Postdoctoral Research Fellow is mainly intended to provide qualification for work in top academic positions. It is a prerequisite that the applicant can carry out the project over the full course of the employment period. No person may hold more than one fixed term position as a Postdoctoral Research Fellow at the same institution.

The position can additionally be assigned to teaching and related work for UiT in an amount equivalent to a maximum 10 % of a full-time employment.

The workplace is at UiT in Tromsø. You must be able to start in the position within a reasonable time after receiving the offer.

Unless special circumstances indicate otherwise, postdoctoral projects shall be planned with stays abroad. The duration should be at least 6 months.

Department of Medical Biology

More than 200 staff members from all over the world have their workplace at the Department of Medical Biology (IMB). The department consists of 13 research groups concentrating on fundamental biomedical research problems, including research on various cancer forms, cardiovascular diseases, the body's immune system and antibiotic resistance. The department is also involved in marine bio-prospecting and testing of new drugs.

IMB provides education for students studying medicine, dentistry, biomedical laboratory sciences, biomedicine and pharmacy.

The position is organized within the recently reappointed Stem Cells, Ageing and Cancer Research Group (SAC). The group aims at understanding malignant haematopoietic stem cell behaviour and regulation. Our goal is the identification of novel therapeutic targets of potential clinical interest. We use a variety of state-of-the-art techniques, including novel mouse genetic tools, stem cells, omics and advanced imaging. Our group has a broad international network and strengthens translational research through established collaborations with the University Hospital of North Norway (UNN).

The position's field of research

Acute myeloid leukaemia (AML) is a highly aggressive haematopoietic malignancy often associated with poor response to chemotherapy and outcome. Our recent work shows that the anti-inflammatory properties of the stem cell and its niche are low in AML, and this may contribute to the origin or progression of malignancy in both in vivo models and patients. In a follow-up project, the successful candidate will contribute now to understand the molecular (genetic/epigenetic) mechanisms underlying the process of HSC malignant transformation, aiming at using this knowledge for better patient treatment. Further project details will be directly discussed with the applicants.

The successful applicant may contribute to the Department's teaching activities (up to 10% of the time). Teaching duties will be allocated based on the applicant's qualifications and the needs of the Department, and may include exam work, teaching seminars, and supervising or assisting in lab courses.

You must submit a description of your past research project(s) and its relevance to the advertised position (maximum 2 pages).

It is expected that the successful candidate shall prepare progress reports some months after commencing employment, and thereafter on a regular basis. The successful candidate will be involved in writing manuscripts and future grants in collaboration with the group leader, Dr. Lorena Arranz.

Contact

For further information about the position, please contact:

  • Group Leader and NCMM Associate Investigator Dr. Lorena Arranz, phone: +47 77 62 08 41, email: [email protected]

Qualifications

To be awarded the position of Postdoctoral Fellow, a Norwegian doctorate in biomedical sciences or equivalent is required, or a corresponding international doctorate degree which is recognised as being equal to the Norwegian doctorate degree.

In addition, for the position announced, the applicant must have prior education and experience in both bioinformatics and wet lab genomics. The position requires good knowledge in the performance, analysis and integration of omics including RNAseq, CHIPseq and/or DNAseq.

Experience with techniques relevant for cell biology research including microscopy and/or flow cytometry, and for molecular biology including qRT-PCR are required.

Experience with mouse models of haematopoietic diseases and knowledge of the HSC microenvironment will be considered advantageous. If not present, the candidate must be willing to acquire the FELASA C certificate as soon as possible, and agree to work with animal models.

Qualification with a PhD is required before commencement in the position. If you’re at the final stages of your PhD, you may still apply if you have submitted your PhD thesis for doctoral degree evaluation within the application deadline. You must submit the thesis with your application. You must have dissertated before the start-up date of the position.

Fluency in English is required.

The candidate must have experience with publishing scientific data, and have at least one or two manuscripts published as first or second author in highly regarded international journals.

Personal skills will be emphasized, including his/her enthusiasm for haematology research and ability to work independently and interactively in a team setting. Importance shall be placed to personal suitability for the position and motivation..

At UiT we put emphasis on the quality, relevance and significance of the research work and not on where the work is published, in accordance with the principles of The San Francisco Declaration on Research Assessment (DORA).

Inclusion and diversity

UiT The Arctic University i Norway is working actively to promote equality, gender balance and diversity among employees and students, and to create an inclusive and safe working environment. We believe that inclusion and diversity is a strength, and we want employees with different competencies, professional experience, life experience and perspectives.

If you have a disability, a gap in your CV or immigrant background, we encourage you to tick the box for this in your application. If there are qualified applicants, we invite least one in each group for an interview. If you get the job, we will adapt the working conditions if you need it. Apart from selecting the right candidates, we will only use the information for anonymous statistics.

We offer

  • Interesting work tasks and science of excellence
  • A highly competitive academic environment with dedicated colleagues
  • International environment and visibility
  • Good career opportunities
  • A large degree of independence in work
  • Flexible working hours and a state collective pay agreement 
  • Pension scheme through the state pension fund 

More practical information for working and living in Norway can be found here.

Application

Your application must include:

  • Cover letter including a short description of interests and reasons for applying for the position
  • Description of your past research project(s) and its relevance to the advertised position (maximum 2 pages)
  • CV containing a complete overview of education, experience, professional work and references
  • Diplomas and transcripts (all degrees)
  • Contact information to 1-2 references
  • Documentation of teaching experience and qualifications, if applicable
  • A list of your academic production
  • Description of your academic production, stating which works you consider most important
  • Academic works, up to four. The doctoral thesis is regarded as one work

In order to achieve a targeted use of the postdoctoral position, and to strengthen the employee’s career development, a development plan must be available no later than three months after the appointment contract is signed. The development plan must be approved by the immediate leader with personnel responsibility.

All documentation to be considered must be in a Scandinavian language or English. We only accept applications and documentation sent via Jobbnorge within the application deadline.

Assessment

The applicants will be assessed by an expert committee. The committee's mandate is to undertake an assessment of the applicants' qualifications based on the written material presented by the applicants, and the detailed description draw up for the position.

The applicants who are assessed as best qualified will be called to an interview. The interview should among other things, aim to clarify the applicant’s motivation and personal suitability for the position. A trial lecture may also be held.

General information

The appointment is made in accordance with State regulations and guidelines at UiT. At our website, you will find more information for applicants.

The remuneration for Postdoctoral research fellow is in accordance with the State salary scale code 1352. A compulsory contribution of 2 % to the Norwegian Public Service Pension Fund will be deducted.

The successful candidate must be willing to get involved in the ongoing development of their department and the university as a whole.

According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

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