Ledig stilling på Universitetet i Oslo

Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Researcher Computational Biology & Gene Regulation

Deadline: 27.10.2020

Job description

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

A researcher position is available in the Computational Biology & Gene Regulation group

led by Anthony Mathelier at the Centre for Molecular Medicine Norway (NCMM), University of Oslo, Nordic EMBL partner for Molecular Medicine. The position is funded through the project “Characterisation of cis-regulatory variations that dysregulate driver microRNAs in cancer” selected by the Norwegian Cancer Society (Kreftforeningen) and is available for two (2) years.

The group was established in 2016 and focuses on gene expression regulation and the mechanisms by which it can be disrupted in human diseases such as cancers. In a nutshell, the group combines experimental and computational approaches to study gene expression dysregulation. The funded project aims at understanding and prioritising patients’ personal variations in cis-regulatory elements with downstream cascading effect on gene expression dysregulation. The selected candidate will perform both experimental and computational work as part of this project. See http://mathelierlab.com for further information about the group.

We seek a highly motivated individual with a track-record of experimental work to study transcription factors and gene expression along with experience with the development of computational pipelines to analyze genomic high-throughput data. We are looking for applicants excited about combining life sciences and computation to analyze gene expression regulation. The successful candidate will be collaborative, independent, with strong enthusiasm for research, and should have experience in programming (mainly Python, R, and bash) dedicated to the analysis of large-scale genomics data. Being familiar with gene expression regulation in general, DNA methylation, and TF binding is a requirement. The candidate will be expected to perform both experimental and computational work. The position is open to applicants with a PhD in molecular biology, computational biology, bioinformatics, or related with post-doctoral experience of maximum 3 years. We offer a stimulating environment with excellent working and social benefits.

Qualification requirements

  • PhD in molecular biology, computational biology, bioinformatics, or a related field
  • Publication records (including 1st authorship) with evidence for writing scientific manuscripts independently
  • Proficiency in programming (Python, R, bash)
  • Experience with experimental work such as cell culture, library preparation, generation of omics data (ATAC-seq, ChIP-seq, DNA methylation, or alike)
  • Documented experience in both experimental generation and computational analysis of their own data leading to peer-reviewed ublication
  • Experience in the field of transcription or epigenetic
  • Ability to collaborate with researchers from different fields and at different career stages
  • Willingness to be part of a team to share knowledge and skills
  • Documented ability to communicate science
  • Knowledge of eukaryotic gene expression regulation
  • Knowledge of molecular biology
  • Experience with analysis of multiple genomics data sets
  • Proficiency in English

We offer

  • salary NOK 563 700 – 594 400 per annum depending on qualifications in position as Researcher (position code 1009)
  • a professionally stimulating working environment
  • attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must include

  • a cover letter outlining motivations, career goals, past achievements, and research interests
  • a CV with list of publications, and
  • 2-3 referees contact information

These should be uploaded as a single PDF document.

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.

Formal regulations

Following the Freedom of Information Act (Offentleglova) § 25, Chapter 2, information about the applicant may be used in the public list of applicants even if the applicant opts out from the entry in the public application list.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results etc.

The University of Oslo aims to achieve a balanced gender composition in the workforce and to recruit people with ethnic minority backgrounds.

Contact information

Inquiries about the position can be directed to Anthony Mathelier

About the application: Nina Modahl

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