Job description

One position as Post-Doctoral Research Fellow is available for 3 years at the Institute of Basic Medical Sciences, Department of Molecular Medicine, Division of Anatomy. The Department of Molecular Medicine conducts research on basic mechanisms of normal cell and organ function, and of disease development.

More about the position

Applications are invited for a Postdoctoral position financed by the Norwegian Research Council. The announced position will be attached to the molecular immunology group, led by Professor Anne Spurkland. The group is focusing on genes controlling T cell activation (https://www.med.uio.no/imb/english/research/groups/immunobiolab/tcell-autoimmune-disease/index.html).

The current project will examine how the Lck adapter TSAd (SH2D2A) modulate and fine tune signalling in activated and experienced T cells. The successful candidate will identify phosphoproteins that are dependent on Lck-TSAd signaling. The work will involve affinity purification mass-spectrometry analysis, gene editing of immune cells using CRISPR-Cas9 and analysis of signaling in immune cells using biochemistry and imaging techniques. The research project is thus within the field of immunology and cellular signalling, and candidates with background in these areas will have an advantage.

The main purpose of post-doctoral research fellowships is to qualify researchers for work in higher academic positions within their discipline.

We are looking for highly motivated and competent candidates with expertise in cellular and molecular immunology with the personal prerequisites to carry out the project within the given timeframe.

Qualification requirements

Applicants must have a degree equivalent to a Norwegian doctoral degree in cellular or molecular biology, immunology or biotechnology. Successful candidates must have submitted their doctoral thesis prior to the application closing date. Appointment is dependent on the public defense of the doctoral thesis being approved.

The successful candidate fill be evaluated on the background of the following criteria:

Criteria that must be met:

• Background (PhD) in molecular immunology, molecular biology or equivalent
• Excellent command of written and oral English

Criteria which is an advantage:

• Experience in molecular immunology
• Experience with bioinformatics or mathematical modelling
• Experience with various biochemistry techniques to study cellular signaling
• Experience in cell analysis by flowcytometry including phosphoflowcytometry
• Experience with CRISPR-Cas9 gene editing in immune cells
• Experience with handling transgenic animals and in isolating and analyzing immune cells from mice
• Good knowledge in standard techniques like cloning and handling of plasmids, mutagenesis of plasmids, gene transfection of eukaryote cells, western blot, qPCR, confocal microscopy
• FELASA C accreditation

Personal skills

Personal suitability and co-operation skills will receive special attention in the selection process.

We offer

• salary NOK 523 200 – 586 900 per annum depending on qualifications in position as Postdoctoral Research Fellow (position code 1352)
• a professionally stimulating working environment
• attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must include:

• Application letter describing how she/he fits the description of the person we seek, including a summary of the applicant's scientific work and interests
• CV summarizing education, positions held, details of academic work, pedagogical and administrative documentation of experience and other qualifying activities
• List of publications, published abstracts, presentations that the applicant wishes to be considered by the evaluation committee
• Copies of educational certificates and transcripts of records
• Names and contact details of 2-3 referees stating relation to candidate, e-mail and telephone number
• The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).
• Top applicants will be called in for an interview.

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system.

In assessing the applications, special emphasis will be placed on the documented, academic qualifications, the project description (whenever this is required in the call for applicants), and the quality of the project as well as the candidates motivation and personal suitability. Interviews with the best qualified candidates will be arranged.It is expected that the successful candidate will be able to complete the project in the course of the period of employment.

Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.

No one can be appointed twice as a Postdoc financed with funds from The Research Council of Norway (NFR).

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results etc.

The University of Oslo aims to achieve a balanced gender composition in the workforce and to recruit people with ethnic minority backgrounds.

Contact information

• Professor Anne Spurkland email: anne.spurkland@medisin.uio.no

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