Job description

A position as postdoctor is available at the Institute of Basic Medical Sciences, University of Oslo from 1.4.22. The position is associated with the research group of professor Heidi Kiil Blomhoff on the project “DNA damage responses regulated by the cAMP/PKA pathway; a toll for improved treatment of pediatric BCP-ALL”. The project is financed by Barnekreftforeningen for a period of three years.

More about the position

The postdoc will take part in a basic project with strong clinical implications. The aim of the project is to identify new targets for improved treatment of B cell precursor acute lymphoblastic leukemia (BCP-ALL). A key feature of the project is modulation of the cAMP/PKA pathway in regulation of cellular processes such as DNA damage responses, oxidative stress, metabolism and autophagy. In addition to experiments on cell cultures of primary ALLs and ALL-derived cell lines, in vivo experiments on an established xenograft model of ALL in NSG mice will have a central role.

We are looking for candidates who have ample experience with cell culturing and assays related to DNA damage responses, metabolism, autophagy, and oxidative stress. It is essential that the candidate has experience with mice models and working in animal facilities.

The main purpose of the fellowship is to qualify researchers for work in higher academic positions within their disciplines. A career development programme is designed for researchers at the beginning of their career at Faculty of Medicine. For more iformation see link.

Qualification requirements

• Applicants must hold a degree equivalent to a Norwegian doctoral degree in cell biology, molecular biology or equal.
• The applicant should be able to work independently, take initiatives and be responsible for own progression
• The applicant should be experienced in molecular/cell biological- and immunological techniques, such as isolation and culturing of cells, cell transfections/siRNA techniques, Western blot analysis, confocal microscopy, and flow cytometry analysis. Experience with methodology relevant for analysis of DNA damage responses, ROS, metbolism and autophagy will also be considered as an advantage.
• It is essential that the applicant has experience with mice models and working in animal facilities.
• The applicant must speak and write English fluently

Personal skills

We are looking for a candidate with the following personal skills:

• Highly motivated
• Collaborative skills
• Organization and communication skills

We offer

• Salary NOK 534 400 – 615 800 per annum depending on qualifications in position as Postdoctoral Research Fellow (position code 1352)
• A professionally stimulating working environment
• Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must include

• The application letter (including a summary of applicant’s scientific work and interest and describing how she/he fits the description of the person we seek)
• CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
• Copies of educational certificates with grades and letters of recommendation. FELASA certification should also be documented.
• Names and contact details of 2-3 referees (names, relation to candidate, e-mail and phone number)
• A complete list of publications and all academic work that the applicant wishes to be considered by the evaluation committee

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

In assessing the applications, special emphasis will be placed on the relevance of the candidate background, both when it comes to the research field and the experimental methods assumed academic and personal ability of the candidate to complete the project within the given timeframe will be considered, as well as social skills for working close with co-workers on the project.

Interviews with the best qualified candidates will be arranged.

Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. We also want to have employees with diverse expertise, combinations of subjects, life experience and perspectives. We will make adjustments for employees who require this.

If there are qualified applicants with special needs, gaps in their CVs or immigrant backgrounds, we will invite at least one applicant in each of these groups to an interview.

Contact information

• Professor Heidi Kiil Blomhoff, e-mail: h.k.blomhoff@medisin.uio.no, Phone +47 22851012

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