Ledig stilling på Universitetet i Oslo

Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Postdoctoral Fellowship in Pancreatic Cancer Metabolism

Deadline: 25.11.2020

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

The Institute of Clinical Medicine (Klinmed) is one of three institutes under the Faculty. Klinmed is responsible for the Faculty's educational and research activities at Oslo University Hospital and Akershus University Hospital. With about 800 employees spread over approximately 425 man-labour years, Klinmed is the university's largest institute. Our activities follow the clinical activity at the hospitals and are spread across a number of geographical areas.

About the position

A position as post-doctoral research fellow is available at the Institute of Clinical Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Department of Gastrointestinal and Children Surgery.

We are searching for a highly motivated candidate, interested in translational medicine. The fellowship is for three years, starting no later than February 2021. Within the period of appointment, it may be agreed that the person appointed shall perform teaching duties, but limited up to 10 % of the post, so that the person’s research work is not hampered.

Project description

The position is linked to the Tumor Biology in Pancreatic Cancer group, led by Prof. Ivar P. Gladhaug. The research group is investigating pancreatic tumor microenvironment especially the stroma-induced biological mechanisms responsible for tumor progression, metabolic remodeling, and chemoresistance in human pancreatic cancer. The project uses a multi-disciplinary approach including in vitro and ex vivo models and human tissue, along with various molecular biology and omics techniques. The project is a collaboration between the Departments of Hepato-pancreato-biliary Surgery, Pathology, and Pharmacology at the University of Oslo and Oslo University Hospital. The relevant techniques are well-established in the group or supported through several ongoing national and international collaborations.

The current project involves identification of metabolic changes and associated molecular mechanisms in human pancreatic tumors that may contribute to overall tumor progression and treatment failure. The project aims to identify new therapeutic targets for pancreatic cancer. The project will utilize human pancreatic tumor-derived biomaterials including tumor biopsies, primary stellate cells (cancer-associated fibroblasts) and cancer cells as well as various commercially available cancer cell lines and fibroblasts. The postdoc will be working primarily with cellular and molecular studies of pancreatic stellate cells, cancer cells, and their interactions.

Qualification requirements

Applicants should hold a PhD degree in molecular cell biology, biochemistry, or pharmacology, equivalent to a Norwegian doctoral degree in Medicine/Life sciences. Successful applicants must have obtained their degree prior to taking on the position. Previous experience in genome editing tools such as CRISPER, in addition to RNA extraction and profiling, is preferable. Experience with genomic analysis and flow cytometry is advantageous (but not required).

Special weight will be accorded to academic skills and demonstrated excellence in research. Good collaborative and communications skills are essential, as well as the ability to work independently. A good command of English is required. Applicants may be called in for an interview.

We are looking for a Researcher who has:

  • High working capacity
  • Strong motivation and interest in solving biological problems
  • Ability to design, plan and interpret original experiments in an independent and innovative manner
  • Excellent oral and written communication skills in English

The main purpose of post-doctoral research fellowships is to qualify researchers for work in top academic positions within their disciplines.

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

We offer

  • A challenging and friendly international working environment with broad expertise in molecular biology and pathology.
  • Access to state of the art facilities and resources for biomedical research in the Department of Pathology and Department of Pharmacology.
  • The position will be placed as SKO 1352 - Postdoc fellow with salary range NOK 526 000 – 608 200 depending on qualifications.
  • Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities.

How to apply

The application must include:

  • Motivation and research plans (max 2 pages)
  • CV (summarizing education, employments within and/or outside of academia)
  • List of publications and academic work that the applicant wishes to be considered by the evaluation committee (not complete articles)
  • Copies of educational certificates and relevant grades
  • Name, email and telephone number of 2-3 referees (describe relation to applicant)
  • The application with attachments should be a single pdf file that includes a covering letter summarizing all of these items.

The application with attachments must be submitted in our electronic recruiting system. International applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results etc.

The University of Oslo aims to achieve a balanced gender composition in the workforce and to recruit people with ethnic minority backgrounds.

Contact information

  • Professor Ivar P. Gladhaug, E-mail: [email protected]
  • For questions regarding the application process, please contact Senior HR adviser Heidi Falch Ecklund, [email protected], Telephone 907 30 348.

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