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Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Postdoctoral fellow in CRISPR gene therapy group

Deadline: 06.12.2021

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

About the position

We announce a two-year extendable postdoctoral fellow position. We welcome applications both from recent PhD graduates and more experienced scientists. Researchers aiming for academic careers are encouraged to apply for independent funding during their first year of employment.

The aim of the Haapaniemi group is to build a gene editing platform that can be used to correct patient-specific mutations in ex vivo cell therapies for genetic immune and other rare childhood diseases. We use high-throughput biology techniques to optimize, develop and understand the CRISPR-Cas9 system that forms the base of the platform, and develop and implement methods to evaluate its safety in a clinical setting. We will use the gene editing technologies for the benefit of the patients in the Nordic hospitals.

Work tasks

The work tasks will depend on your interest and scientific background and will generally include one or more of the following:

  • Design and conduct custom CRISPR experiments and screens
  • Design and optimize high-throughput biology experiments in robotics platforms
  • Set up custom Next Generation Sequencing libraries and technologies
  • Set up flow cytometry – based immunological assays
  • Set up functional assays for immune cells
  • Supervise students and technicians in designing and conducting molecular biology experiments

Qualification requirements

Postdoctoral fellow, position code 1352:

  • PhD, BA or MA (expected PhD graduation date within 6 months of application closing date)
  • Documented research experience in one or more of the following fields: immunology or stem cell biology, high-throughput biology and/or Next Generation Sequencing method development, DNA repair and genome stability.
  • At least one published first-author paper
  • Fluent oral and written English communication skills

The following qualifications will count in the assessment of the applicants:

  • Experience with any of the following techniques: multi-color flow cytometry, Next Generation Sequencing library preparation, immune cell culture and transfection, or experience with mouse work.
  • Experience in genetic analyses
  • Python, Perl, R or other relevant programming language skills

Personal skills

  • Organized, meticulous and independent
  • Ability to communicate and work in shared multidisciplinary projects
  • Willing to supervise students and staff

We offer

  • Salary NOK 534 400 - 615 800 per annum depending on qualifications
  • An exciting, translational project where your strong basic science background can directly benefit our sickest patients
  • Opportunity to shape a new laboratory
  • Upon mutual agreement, the possibility to transition into a researcher position (position code 1109) after the postdoctoral period
  • Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must include

  • Cover letter (statement of motivation, summarizing scientific work and research interest)
  • CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
  • Copies of educational certificates (academic transcripts only)
  • List of publications
  • List of 3 reference persons (name, relation to candidate, e-mail and phone number)

Please deliver the application with attachments in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.

In assessing the applications, special emphasis will be placed on the documented, academic qualifications as well as the candidate’s motivation and personal suitability. We will arrange interviews with the best qualified candidates. We expect that the successful candidate will be able to complete the project during the period of employment.

Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. We also want to have employees with diverse expertise, combinations of subjects, life experience and perspectives. We will make adjustments for employees who require this.

If there are qualified applicants with special needs, gaps in their CVs or immigrant backgrounds, we will invite at least one applicant in each of these groups to an interview.

Contact information

Inquiries about the positions can be directed to group leader Dr. Emma Haapaniemi, [email protected]

Inquiries about application can be directed to HR-adviser Nina Modahl: [email protected]

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