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Researcher in immunology
Universitetet i Oslo
The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.
The Institute of Basic Medical Sciences overall objective is to promote basic medical knowledge in order to understand normal processes, provide insight into mechanisms that cause illness, and promote good health. The Institute is responsible for teaching in basic medical sciences for the programmes of professional study in medicine and the Master's programme in clinical nutrition. The Institute has more than 300 employees and is located in Domus Medica.
Applicants are invited for a 2 year position as Researcher in immunology to be based at the Department of molecular medicine, University of Oslo.
The announced position will be attached to the molecular immunology group, led by Professor Anne Spurkland. The group is focusing on genes controlling T cell activation. The current project will examine how the Lck adapter TSAd (SH2D2A) affects signalling in activated and experienced T cells. The successful candidate will investigate the interactome of TSAd and explore whether the Lck-TSAd interaction affects chimeric antigen receptor (CAR) signalling in T cells. The work will involve affinity purification mass-spectrometry analysis, gene editing of immune cells using CRISPR-Cas9 and generation and analysis of CARs. The research project is thus within the field of immunology and cellular signalling, and candidates with background in these areas will have an advantage. The project may lead to improved cancer immunotherapy using CAR-T cells.
More about the position
We are looking for highly motivated and competent candidates with expertise in cellular and molecular immunology with the personal prerequisites to carry out the project within the given timeframe.
Applicants must hold a degree equivalent to a Norwegian doctoral degree in cellular or molecular immunology. Successful candidates must have submitted their doctoral thesis prior to the application closing date. Appointment is dependent on the public defense of the doctoral thesis being approved.
The following qualifications are absolutely required (candidates lacking these will not be considered for the position):
- Background (PhD) in cellular or molecular immunology
- Experience with various biochemistry techniques to study cellular signaling
- Excellent command of written and oral English
Candidates with the following qualifications will be preferred:
- Experience in cell analysis by flow cytometry including phospho-flow cytometry
- Experience with CRISPR-Cas9 gene editing in immune cells
- Experience with CAR T cells
- Experience with handling transgenic animals and in isolating and analyzing immune cells from mice
- Good knowledge of basic gene technology methods, such as PCR, gene cloning and plasmid handling.
- FELASA C accreditation
Personal suitability and co-operation skills will receive special attention in the selection process.
- salary NOK 544 400 – 648 700 per annum depending on qualifications in position as Researcher (position code 1109)
- a professionally stimulating working environment
- attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities
How to apply
The application must include
- cover letter (statement of motivation, summarizing scientific work and research interest)
- CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
- copies of educational certificates (academic transcripts only)
- a complete list of publications
- list of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)
The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).
In assessing the applications, special emphasis will be placed on the documented, academic qualifications, and the candidates motivation and personal suitability. Interviews with the best qualified candidates will be arranged.
It is expected that the successful candidate will be able to complete the project in the course of the period of employment.
According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.
Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. Furthermore, we want employees with diverse professional expertise, life experience and perspectives.
If there are qualified applicants with disabilities, employment gaps or immigrant background, we will invite at least one applicant from each of these categories to an interview.
Apply for position