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Laboratory engineer for organoid research

Deadline: 29.05.2023

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

The Institute of Basic Medical Sciences overall objective is to promote basic medical knowledge in order to understand normal processes, provide insight into mechanisms that cause illness, and promote good health. The Institute is responsible for teaching in basic medical sciences for the programmes of professional study in medicine and the Master's programme in clinical nutrition. The Institute has more than 300 employees and is located in Domus Medica.

About the position

The Hybrid Technology Hub Centre of Excellence at Oslo University Hospital and University of Oslo, Norway is currently accepting applications for a 2 year position as a laboratory engineer to work on stem cell derived organoids (100% position).

The Centre headed by Prof. Stefan Krauss is located at the Institute of Basic Medical Sciences at University of Oslo, with partners at the University of Glasgow and Imperial College, London. The overall objective of the Centre is to develop innovative human 3D models (3D organoids and organ-on-chip systems) for experimental drug testing and animal testing replacement.

The laboratory engineer, funded by the research council of Norway, will participate in the development of advanced in vitro liver organoids for disease modelling and drug testing. The work will include culture and differentiation of human embryonic and induced pluripotent stem cells, culture of 3D organoids, and culture of 3D organoids in a microfluidic platform under various conditions including drug testing. The laboratory engineer will also assist with RNA/DNA isolation, preparation of samples sequencing and ELISA.

Work tasks

  • Human stem cell culture and differentiation, including organoid/spheroid formation, culture of cells and organoids/spheroids in a microfluidic system
  • Assays, including drug testing, on organoids/spheroids
  • Molecular biology experiments including DNA/RNA isolation, qPCR, sample preparation for sequencing and ELISA
  • Contributing to the day-to-day running of the lab, including ordering system and cleaning routines
  • Maintaining excellent laboratory notebooks (manual and/or electronic) to document all aspects of the experimental work

Qualification requirements

  • A Bachelor’s or Master’s degree in molecular biology, biochemistry, genetics, biotechnology or a similar subject is required. Real competence with relevance to the tasks in question can compensate for the education requirement. Furthermore, relevant practical work experience may be required.
  • Minimum of one-year laboratory experience is required
  • Experience with human or mouse cell culture is required
  • Experience with basic molecular biology is required
  • Experience with human stem cell culture and organoids is an advantage
  • Experience in flow cytometry is an advantage
  • Good knowledge in cell biology, developmental biology and histology is an advantage.
  • Fluency in Norwegian is not required but is considered an advantage

Personal skills

  • Independent work and troubleshooting
  • Ability to learn quickly and work in a fast-paced multidisciplinary environment
  • Team player
  • Fluent in both spoken and written English
  • Flexibility of working on weekends, (2-3 hours)

We offer

  • salary NOK 509 300 - 575 400 per annum depending on qualifications in a position as (Laboratory engineer), position code 1085
  • attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities
  • A positive and stimulating international working environment with experienced staff
  • Salary according to agreement
  • Competitive conditions
  • Flexible working hours

How to apply

The application must include:

  • cover letter statement of motivation
  • CV (summarizing education, positions and academic work)
  • copies of educational certificates (academic transcripts only)
  • evt. documentation of english proficiency
  • list of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)

The application (evt.) with attachments must be delivered in our recruiting system.

Formal regulations

Interviews with the best qualified candidates will be arranged.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition.Furthermore, we want employees with diverse professional expertise, life experience and perspectives.

If there are qualified applicants with disabilities, employment gaps or immigrant background, we will invite at least one applicant from each of these categories to an interview.

Contact information

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