Job description

A two year full-time position for a Postdoctoral research Fellow (SKO 1352) is available at the K.G. Jebsen Coeliac Disease Research Centre.

The position is affiliated with the research group of Professor Ludvig M. Sollid at the KG Jebsen Coeliac Disease Research Centre, Department of Immunology, Institute of Clinical Medicine, Faculty of Medicine and the project will be supervised by Dr.Jorunn Stamnæs.

More about the position

The project will explore the use of limited clinical biopsy material for global proteome analysis by mass spectrometry. Patients with coeliac disease develop intestinal inflammation when they ingest gluten. Disease severity is typically assessed from histological changes. We have demonstrated that proteome analysis of tissue biopsy material gives a more nuanced picture of disease status and can reveal inflammation not evident to the pathologists. The aim this project is to identify and verify tissue protein signatures that can serve as markers for active disease or disease remission in particular in patients where histological classification is challenging or inadequate. The project may also explore approaches to obtain spatially resolved tissue proteome information.

A main goal of the K.G. Jebsen Coeliac Disease Research Centre is to translate advances in the basic understanding of the pathogenesis of coeliac disease to the clinic: to improve disease diagnostics, to implement novel treatments and to identify new therapeutic targets for this common disease. This project will contribute to development of improved diagnostics and approaches to assess patient treatment status.

The successful applicant will join a thriving and highly multidisciplinary research environment that combines basic, translational and clinical research on immune mediated diseases with particular focus on coeliac disease and autoimmunity. For more details about the research group and centre, please visit the centre web site. We have through the proteomic core facility at Oslo University Hospital access to state of the art instruments and research infrastructure.

The main objective of appointment to the position of Postdoctoral Fellow is to qualify researchers for work in top academic positions within their respective area of study.

Qualification requirements

• The successful candidate must hold a PhD in biochemistry, systems biology, immunology or equivalent and have laboratory experience from sample preparation strategies for bottom-up proteomics analysis, quantitative proteomics workflows and data-analysis.
• Experience with statistical approaches and programming relevant for analysis “omics” datasets is a strong advantage. Experience from research projects that involve biological interpretation of or validation of omics data generated from human cells or tissues is beneficial.
• The candidate must be fluent in written and spoken English.
• We are looking for a motivated and structured candidate with strong laboratory skills and good collaborative qualities.

We offer

• A challenging and friendly working environment
• Salary NOK 497 000 to NOK 597 400 per annum depending on qualifications as Postdoctoral Research Fellow (position code 1352).
• Attractive welfare benefits and generous pension arrangement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application should include:

• Application letter, including a ½ page motivation statement and research interests.
• CV (summarizing education, positions, academic work, scientific publications and
• other relevant activities)
• Copies of educational certificates and grades.
• Letters of recommendation
• A list of publications and academic work that the applicant wishes to be considered by the evaluation committee (publications themselves should not be enclosed).
• Names and contact details of 2-3 referees (name, relation to candidate, e-mail and telephone number).

The application with attachments must be delivered in our electronic recruiting system.

The application with the required attachments should preferably be complied to as few files as possible, preferably 1-2 files.

Foreign applicants are advised to attach an explanation of their University's grading system. Please remember that all documents should be in English or a Scandinavian language.

Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. We also want to have employees with diverse expertise, combinations of subjects, life experience and perspectives. We will make adjustments for employees who require this.

If there are qualified applicants with special needs, gaps in their CVs or immigrant backgrounds, we will invite at least one applicant in each of these groups to an interview.

Preferred starting date: April, 2021.

Contact information

• Dr. Jorunn Stamnæs, e-mail: jorunn.stamnas@medisin.uio.no
• Professor Ludvig M. Sollid, e-mail: l.m.sollid@medisin.uio.no
• HR-advisor Karoline Berg-Eriksen (questions regarding the online application form), e-mail: karoline.berg-erksen@medisin.uio.no

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