Ledig stilling på Universitetet i Oslo

Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Post-doctoral position in functional genomics and cancer research

Deadline: 15.09.2022

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7 500 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Job description

A two-year extendable post-doctoral position is available in the group of Dr. Biswajyoti Sahu at the Centre for Molecular Medicine, Norway. We are seeking a highly motivated and talented individual for working in the field of functional epigenomics in cancer research and transcriptional regulation. We offer a position in an ambitious, multi-disciplinary and well-resourced group that is comprised of both wet-lab and computational scientists. Our group investigates the interplay between transcription factors and oncogenes using a rationale multi-cancer approach and modern genome-wide methods for regulatory genomic features and chromatin architecture. We utilize a wide range of cutting-edge functional genomics approaches, from ChIP-seq, CUT&RUN and HiChIP to single-nuclei multiome RNA-seq and ATAC-seq assays, epigenetics analysis using single-molecule nanopore sequencing, as well as CRISPR-based approaches for genome editing.

Work tasks

The work tasks will depend on your skills and scientific background and will generally include one or more of the following:

  • Designing and performing genome-wide functional genomics experiments in mammalian cells using modern methods such as ATAC-seq, HiChIP, ChIP-seq, as well as CRISPR-based approaches.
  • Developing and adapting cutting-edge functional epigenomics assays based on Illumina and/or long-read nanopore sequencing.
  • Computational analysis and integration of functional genomics datasets from next-generation sequencing methods.
  • Supervision of students and technicians in designing and conducting molecular biology experiments.

Qualification requirements

Postdoctoral fellow, position code 1352:

  • A PhD degree in any relevant field of life sciences
  • Documented research experience in one or more of the following fields: transcriptional regulation, cancer biology, functional genomics and/or epigenomics
  • At least one published first-author paper
  • Excellent written and oral communication skills in English

Ability to work independently as well as operating as a team player in multi-disciplinary projects is a must, and willingness to supervise students and staff is important. Prior experience in the following is considered a plus: mammalian cell-based assays, functional genomics experiments, generating next-generation sequencing libraries, and/or analysis of high-throughput functional genomics datasets, knowledge about relevant programming languages (Python, Perl, R). A good understanding of biochemistry, genomics experiments and bioinformatics is expected. Candidates with proven track record in terms of publications will be given preference.

We offer

  • Salary NOK 544 400 - 626 300 per annum depending on qualifications
  • An exciting project utilizing cutting-edge functional genomics methods to understand molecular basis of human cancer
  • A position in an ambitious, multi-disciplinary and well-resourced group that is comprised of both wet-lab and computational scientists
  • Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities.

For more information about our current research operations and our latest publications (including Sahu et al, Nature Genetics, 2022; Sahu et al, Oncogene, 2021), see here. The new lab at the NCMM Norway will open in September 2022, and the position is available immediately.

How to apply

The application must include

  • Cover Letter stating motivation and research interests
  • A recent CV with a complete list of scientific publications
  • Copies of certificates and grades with explanation of the grading system
  • Two–three reference letters with contact details of the referees (name, relation to candidate, e-mail and telephone number)

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.

Interviews with the best qualified candidates will be arranged. Applications will be considered on a rolling basis till a suitable candidate is found.

Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. Furthermore, we want employees with diverse professional expertise, life experience and perspectives.

If there are qualified applicants with disabilities, employment gaps or immigrant background, we will invite at least one applicant from each of these categories to an interview.

Contact information

Inquiries about the positions can be directed to Group Leader Dr. Biswajyoti Sahu: [email protected]

Inquiries about application can be directed to HR-adviser Nina Modahl: [email protected]

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