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PhD Research Fellow in molecular biology and biochemistry

Deadline: 16.04.2023

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

The Institute of Basic Medical Sciences overall objective is to promote basic medical knowledge in order to understand normal processes, provide insight into mechanisms that cause illness, and promote good health. The Institute is responsible for teaching in basic medical sciences for the programmes of professional study in medicine and the Master's programme in clinical nutrition. The Institute has more than 300 employees and is located in Domus Medica.

Job description

Applications are invited for a 3-year position as a Research Fellowship as Ph.D. candidate at the Institute of Basic Medical Sciences, University of Oslo, Norway. The position is part of a cross disciplinary program focusing on skeletal muscle atrophy in cancer cachexia. The main purpose is to investigate the role of transcription factors involved in pancreatic cancer-induced muscle atrophy by using both in vitro (co-cultures with C2C12 and cancer cells) and in vivo models (transgenic mice).

More about the position

Research activities will take place jointly in the groups headed by Prof. Jason Matthews (Matthews Lab) and Prof. Jérôme Ruzzin (Ruzzin lab) with expertise in cancer and skeletal muscle research, respectively.

We are interested in qualified and highly motivated applicants and offer competence development within skeletal muscle and cancer research in a stimulating academic environment.

The research fellow must take part in the Faculty’s approved Ph.D. program and is expected to complete the project within the set fellowship period. The main purpose of the fellowship is research training leading to the successful completion of a Ph.D. degree.

Two months after employment the applicant must, in collaboration with their two supervisors, prepare a complete project description to be attached to the application for admission to the doctoral program.

For more information, please visit our web site .

Qualification requirements

  • Applicants must hold a Master’s degree in a relevant field such as molecular biology / biochemistry, minimum grade B (ECTS grading scale) or equivalent. The Master’s degree must include a thesis of at least 30 ECTS and be in a subject relevant to the position, such as biology, medicine, molecular biology, pharmacology & toxicology, or biochemistry.
  • Fluent oral and written communication skills in English are expected.
  • Previous experience with molecular and cell biology is required.
  • Experience with cell culture and/or mouse experiments is necessary.
  • Authorization to work with animal research is positive (LAS301).
  • Contribution to peer-reviewed article publication will be considered as highly positive.
  • Ability to work independently as well as in a team.

Personal skills

We are seeking a highly motivated, ambitious, and skilled candidate. The candidate must be able to work independently, but also have good interpersonal skills and desire to contribute to strengthening the research environment.

Work responsibilities:

  • Laboratory work such as RNA and DNA isolation, PCR, rt-qPCR and Western blot analyses, RNA sequencing, ELISA.
  • Cell culture studies including co-culture studies with C2C12 myoblasts/myotubes and cancer cells.
  • Mouse experiments (including breeding and maintenance of genetically modified mouse strains).
  • Statistical analyses, processing, and data presentation.

We offer

  • Salary NOK 501 200- 544 400 per annum depending on qualifications in a position as PhD Research fellow, (position code 1017)
  • Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must include

  • Cover letter statement of research interests and motivation for applying for this position
  • CV (summarizing education, positions and academic work)
  • Copies of educational certificates (academic transcripts only)
  • Documentation of English proficiency (for information on required documentation, see information on this webpage)
  • A complete list of publications and academic works
  • List of reference persons: 3 references (name, relation to candidate, e-mail and phone number)

The application with attachments must be delivered in our electronic recruiting system, please follow the link: “Apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

When evaluating the application, emphasis will be given to the applicant’s academic and personal prerequisites to carry out the project. Applicants may be called in for an interview.

Formal regulations

Please see the guidelines and regulations for appointments to Research Fellowships at the University of Oslo.

No one can be appointed for more than one PhD Research Fellowship period at the University of Oslo.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results etc.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. Furthermore, we want employees with diverse professional expertise, life experience and perspectives.

If there are qualified applicants with disabilities, employment gaps or immigrant background, we will invite at least one applicant from each of these categories to an interview.

Contact information

  • Professor Jason Matthews: jason.matthews@medisin.uio.no
  • Professor Jérôme Ruzzin: jerome.ruzzin@medisin.uio.no

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