Head engineer - Advanced Systems Immunology and In Vivo Imaging
Deadline: 07.11.2026
Publisert
The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 26 500 students and 7 200 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.
The Institute of Clinical Medicine (Klinmed) is one of three institutes under the Faculty. Klinmed is responsible for the Faculty's educational and research activities at Oslo University Hospital and Akershus University Hospital. With about 900 employees spread over approximately 425 man-labour years, Klinmed is the university's largest institute. Our activities follow the clinical activity at the hospitals and are spread across a number of geographical areas.
About the position
A 12-month long position for a highly skilled and motivated Head Engineer is available in the Laboratory of Immunoregulation and T cell biology, led by Associate Professor Johanne T. Jacobsen at the Institute of Clinical Medicine, University of Oslo.
Our ability to fight off infections and respond to vaccines depends on the immune system's capacity to produce powerful and long-lasting antibodies. This critical process of immune memory is forged within microscopic structures in our lymph nodes called germinal centers (GCs). Our laboratory is dedicated to understanding the fundamental rules that govern the output of the GC. We investigate how different types of immune cells communicate and cooperate within the germinal center to ensure the production of high-quality, durable immunity. This position offers a unique opportunity to contribute directly to research with significant translational potential.
Responsibilities
The technician will be entrusted with some responsibility for the operation of unique technological workflows.
Intravital 2-Photon Microscopy: Key responsibilities include animal surgery (mouse models), longitudinal imaging window implantation and imaging acquisition and live cell tracking using Imaris Software.
Single-Cell Multi-Omics: involves library preparation using both SMART-seq2 (for full-length transcript coverage) and the BD Rhapsody system (for high-throughput, multimodal analysis of RNA, AbSeq, BCR, and TCR).
Beyond the core platforms, the candidate will support several other core techniques in the group such as antibody production and Adeno Associated Virus (AAV) production for the generation of transgenic mice.
Qualifications
We seek a candidate who is not only technically proficient but also intellectually engaged and driven to push the boundaries of what is possible. The candidate must be capable of working with a high degree of autonomy and taking ownership of the lab's core technological infrastructure.
Qualification requirements
Relevant education from a university or university college at a minimum level equivalent to a bachelor's degree.
Extensive, documented hands-on experience with in vivo mouse models, including proficiency in surgical procedures.
FELASA certificate (or equivalent).
Demonstrable expertise in advanced cellular or molecular biology techniques.
Experience in either (a) high-resolution microscopy (confocal/2-photon) or (b) next-generation sequencing library preparation.
Full professional fluency in English (written and spoken), the working language of the lab.
Desired qualifications
A Master of Science (MSc) degree in Immunology, Molecular Biology, Cell Biology, Biomedical Science, or a related field.
Direct, hands-on experience with 2-photon intravital microscopy.
Practical experience with single-cell RNA-sequencing workflows (e.g., SMART-seq2, 10x Genomics, or BD Rhapsody).
Experience with immune repertoire (BCR/TCR) sequencing library preparation.
Experience with computational analysis of imaging or sequencing data.
Experience with mouse handling and has a FELASA certificate.
Personal qualities
Independence and Drive: A highly self-driven individual, capable of managing complex, multi-stage experiments independently and taking ownership of projects from start to finish.
Meticulous and Resilient: A rigorous, exacting, and structured approach to experimental work is paramount. The role requires a creative and persistent mindset for troubleshooting complex technical challenges.
Collaborative and Communicative: Excellent communication skills and a collaborative spirit are essential for working effectively within our international team.
Organizational Prowess: Superb organizational skills, including experience with digital lab notebooks and the management of large, complex datasets, are required to handle the data flow from our multi-omics pipelines.
Personal suitability will be emphasized in the recruitment process.
We need different perspectives in our work
UiO is an open and internationally oriented comprehensive university that strives to be an inclusive and diverse workplace and academic environment. You can read more about UiO’s work on equality, inclusion, and diversity at uio.no.
We fulfill our mission most effectively when we draw upon our variety of experiences, backgrounds, and perspectives. We are looking for great colleagues—could you be the next one?
We will do our best to accommodate your needs. Relevant adjustments may include modifications to working hours, task adaptations, digital, technical, or physical adjustments, or other practical measures.
If you have an immigrant background, a disability, or CV gaps (Norwegian), we encourage you to indicate this in the job application portal. We always invite at least one qualified candidate from each group for an interview. In this context, disability is defined as an applicant who identifies as having a disability that requires workplace or employment-related accommodations. For more details about the requirements, please refer to the Employer portal (Norwegian).
The selections made in the job application portal are used for anonymized statistics that all state employers include in their annual reports.
We hope you will apply for the position with us.
We offer
Exciting and meaningful tasks in an organization with an important societal mission, contributing to knowledge development, education, and enlightenment that promote sustainable, fair, and knowledge-based societal development.
World-Class Research Environment in a Vibrant City. This position represents a unique chance to be at the absolute forefront of systems immunology, working with pioneering technologies in a highly ambitious, well-funded, and supportive research group.
A workplace with good development and career opportunities.
Membership in the Statens Pensjonskasse, which is one of Norway's best pension schemes with beneficial mortgages and good insurance schemes.
Salary in position as Head Engineer, position code 1087 in salary range NOK from 620.000 - to 670.000, depending on competence and experience. From the salary, 2 percent is deducted in statutory contributions to the State Pension Fund.
Read more about the benefits of working in the public sector at Employer Portal.
Application
Your application should include:
Application letter: This should detail your motivation for applying and specifically address how your hands-on technical experience with the advanced techniques mentioned (in vivo imaging, scRNA-seq, etc.) makes you an ideal candidate for this role.
CV: A comprehensive summary of your education, positions, technical skills, and publication list (if applicable).
Transcripts and certificates: Copies of your academic transcripts (Master's and Bachelor's).
Contact information for 2-3 professional references.
Documentation of English proficiency.
Application with attachments must be submitted via our recruitment system Jobbnorge, click "Apply for the position".
When applying for the position, we ask you to retrieve your education results from Vitnemålsportalen.no. If your education results are not available through Vitnemålsportalen, we ask you to upload copies of your transcripts or grades. Please note that all documentation must be in English or a Scandinavian language.
General information
The best qualified candidates will invited for interviews.
Applicant lists can be published in accordance with Norwegian Freedom of Information Act § 25. When you apply for a position with us, your name will appear on the public applicant list. It is possible to request to be excluded from this list. You must justify why you want an exemption from publication and we will then decide whether we can grant your request. If we cannot, you will hear from us.
