LEDIG STILLING VED UNIVERSITETET I BERGEN

Researcher - Department of Biomedicine

Deadline: 01.09.2022

University of Bergen

The University of Bergen is a renowned educational and research institution, organised into seven faculties and approximately 54 institutes and academic centres. Campus is located in the centre of Bergen with university areas at Nygårdshøyden, Haukeland, Marineholmen, Møllendalsveien and Årstad.


There are five departments and seven centres at Faculty of Medicine.


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Researcher

At the Faculty of Medicine, Department of Biomedicine, a full-time (100 %) temporary position as a researcher is available. The position is external financed by research grant of the Norwegian Research Council, and part of the research project “High-dimensional analysis of AXL- mediated immunotherapy resistance: Clinical translation for personalized medicine”. The project has temporary financing for one year and seven months.

About the project/work tasks:

The AXL receptor tyrosine kinase is a key mediator of acquired resistance to anti-cancer therapy. AXL signaling regulates both tumor intrinsic and innate immune mechanisms in the tumor microenvironment that engender epithelial plasticity and subvert anti-tumor immunity. The primary objective of this project is to characterize how AXL receptor signaling regulates tumor intrinsic resistance to immunotherapy. The central hypothesis is that novel AXL complexes with unique signal transduction attributes support T cell resistant cell states. We address this through state-of-the-art experimental approaches comprising multiplex imaging of AXL complexes, high dimensional proteomic signal transduction analysis, murine models of next generation immunotherapy and single-cell mapping of phenotypic-spatial features of the tumor microenvironment.

Work tasks:

  • characterize how novel AXL receptor complexes affect cell signaling
  • conduct experiments that to measure AXL receptor interactions with SH2 proteins and determine phosphorylation-mediated signal transduction

Qualification and personal qualities:

  • the applicant must hold a relevant PhD or equivalent doctoral degree, and have at least three years of postdoctoral experience with a good scientific track record
  • the successful applicant must have extensive experience in advanced multiplex imaging techniques, such as super resolution microscopy, TIRF imaging and the study of phosphorylation-mediated signal transduction mechanisms
  • the candidate should be able to work independently and interactively in a team setting, be motivated and responsible, and have enthusiasm for research
  • personal skills will be emphasized
  • the candidate must be fluent in spoken and written English

We can offer:

  • an exciting international scientific work environment
  • salary NOK 593 000 (code 1109/salary scale 24.8), specialist NOK 615 000 (code 1109/salary scale 24.10) gross p.a. for a fulltime position; following ordinary meriting regulations
  • enrolment in the Norwegian Public Service Pension Fund
  • good welfare benefits

Your application must include:

  • a brief letter of application stating your motivation for the position, why you are applying and why this position is perfect for you
  • an overview of your education and work experience (CV)
  • witnessed copies of diplomas and relevant certificates (applicants with education from other countries than Norway must enclose diplomas in both the original language and authorized translations)
  • publications and academic work (max 10) and a list of these
  • your PhD thesis (in PDF)
  • two referees (name and contact information)

It is very important that each of the scholarly works on which the committee should place special emphasis, is attached in its entirety.

The following premise forms the basis for the post as researcher:

  • the researcher will be a member of the research group of which the topic/project belongs to
  • the salary shall if possible be 100 % covered by external financing
  • the researcher shall actively contribute to attract external funding to the research project, both for her/his own position and other positions, from the Research Council of Norway, EU and other sources
  • the researcher is expected to have her/his research activity financed by the project of the researcher and the projects of the associated research group
  • the Head of Department may allocate work for the Researcher related to specific research projects
  • the researcher may participate in committee work and other administrative tasks within the University of Bergen
  • the researcher has no teaching duties, but is expected to supervise master students and PhD candidates when this is a natural part of the research activity of the research group
  • the researcher may apply for competence promotion according to the regulations for promotions
  • the basis for the position ceases if no further project funding and new law on state officials etc. on dismissal and preferential rights will be applied to permanent employees

General information:

Further information about the position can be obtained from:

The state labour force shall reflect the diversity of Norwegian society to the greatest extent possible. People with immigrant backgrounds and people with disabilities are encouraged to apply for the position.

The University of Bergen applies the principles of public access to information when recruiting staff for academic positions. Information about applicants may be made public even if the applicant has asked not to be named in the list of persons who have applied. The applicant must be notified if the request to be omitted is not met.

For further information about the recruitment process, click here.

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