Ledig stilling på Universitetet i Oslo

Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Researcher Position in Breast Cancer Nuclear Architecture

Deadline: 20.10.2020

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

The Institute of Basic Medical Sciences overall objective is to promote basic medical knowledge in order to understand normal processes, provide insight into mechanisms that cause illness, and promote good health. The Institute is responsible for teaching in basic medical sciences for the programmes of professional study in medicine and the Master's programme in clinical nutrition. The Institute has more than 300 employees and is located in Domus Medica.

Job description

A RESEARCHER POSITION (SKO 1109) in breast cancer nuclear architecture is available for 3 years at the Institute of Basic Medical Sciences, Department of Molecular Medicine, University of Oslo. The position is funded by the Norwegian Cancer Society.

The position is in the group of Professor Philippe Collas (www.collaslab.org) whose research focuses on the study of chromatin and nuclear architecture in stem cells and cancer cells. The project aims to study nuclear organization and 3D genome conformation in a model of breast cancer cell transformation/metastasis, using molecular, cell biology and genomics functional approaches.

More about the position

The work will involve designing and carrying out functional cell/molecular biology experiments to understand mechanisms driving changes in chromatin and nuclear architecture during breast cancer cell malignant transformation. The work will also involve manuscript writing, report writing, grant writing, supervision of PhD students and collaborator contacts.

The researcher will be able to draw on expertise of the group in high-throughput genomics, bioinformatics and advanced molecular/cell biology in cancer and non-cancer cell models.

Qualification requirements

The selected candidate must demonstrate scientific background and experience in functional aspects of breast cancer biology, cell signaling, gene regulation, nuclear architecture including the nuclear envelope and nuclear envelope-chromatin relationships, and chromatin biology. From a technical aspect, s/he will be able to document experience in carrying out mechanistic studies, culture of human primary cells and explants, strong molecular and cell biology skills, advanced live-cell microscopy and image analysis, proteomics and transcriptomics and 3D genome analysis.

Other criteria which must be met:

  • Ph.D. and at least one postdoc period
  • Documented experience in breast cancer cell biology and nucleus nuclear envelope biology
  • Ability to take initiatives and follow through
  • Ability to develop and implement own ideas
  • Ability to troubleshoot

Criteria to be considered as an advantage:

  • Documented ability to obtain own external funding
  • Prior daily supervision of students in the laboratory

Personal skills

  • Motivation
  • Ability to work independently and collaborate
  • Pedagogical abilities
  • Personal suitability to the work environment
  • Excellent communication skills
  • Excellent spoken and written English

We offer

  • Salary NOK 523 200 – 583 900 per annum depending on qualifications in position as Researcher (position code 1109)
  • A professionally stimulating and friendly working environment
  • Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must include

  • Application letter staring i) your motivation for the position, ii) reasons why you fit the position, and iii) previous research accomplishments highlighting the significance of your work
  • CV summarizing education, positions, relevant work experience and scientific skills
  • Complete list of publications including published abstracts, and list of seminar invitations (do not upload the publications, abstracts or theses with the application).
  • Copies of educational certificates (MSc and PhD, or equivalents) and transcripts.
  • Note: foreign applicants are advised to attach an explanation of the grading system in their university.
  • 3 references with name, relation to the candidate, email and phone number.

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

Formal regulations

Please see the guidelines and regulations for appointments of Researchers at the University of Oslo.

According to the Norwegian Freedom of Information Act, information about the applicant may be made public even when the applicant has requested non-disclosure.

The University of Oslo has an agreement for all employees aiming to secure rights to research results.

The University of Oslo aims to achieve a balanced gender composition in the workforce and to recruit people with ethnic minority backgrounds.

Contact information

  • Professor Philippe Collas; Email: [email protected]
  • For more information on the research group, go to www.collaslab.org

Apply for position

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