Ledig stilling på Universitetet i Oslo
Researcher - Institute of Clinical Medicine
Universitetet i Oslo
The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.
The Institute of Clinical Medicine (Klinmed) is one of three institutes under the Faculty of Medicine.
Klinmed is responsible for the Faculty's educational and research activities at Oslo University Hospital and Akershus University Hospital. With about 850 employees spread over approximately 425 man-labour years, Klinmed is the university's largest institute. Our activities follow the clinical activity at the hospitals and are spread across anumber of geographical areas.
Researcher Cellular immune response to SARS-CoV-2 VoC and third and fourth corona vaccination in immunocompromised patients
An 18-month position as researcher (position code 1109) is available in a multidisciplinary group at the KG Jebsen Centre for B-cell malignancies, Department of Immunology, Institute of Clinical Medicine, University of Oslo. The applicant will join our successful and highly talented multidisciplinary team that this year has published covid-research in high impact journals including NEJM, EHJ, JAMA Neurology (in press), Lancet Rheumatology (in press) and JNNP. The position is one of eight hospital or Uni positions that are funded by the Coalition for Epidemic Preparedness Innovations (CEPI), a global partnership to accelerate the development of vaccines and is a regional partnership between the OUH, Norwegian National Institute of Health (FHI), Diakonhjemmet hospital, Akershus University Hospital. The positions will be in the research group of Professor Ludvig A. Munthe.
More about the position
The successful applicant will work in Lab at the KG Jebsen Centre that is situated in the Department of immunology at the Oslo University Hospital-Rikshospitalet in close proximity to core facilities. In addition, the person will stain, run and analyze samples at the mass cytometry core facility at Norwegian Institute of Public Health (NIPH) in a multidisciplinary team including specialization in infection and immunity and cellular proteomics.
The work will be embedded in established studies on immune responses in infection and extensive experience with other RNA viruses (influenza especially), autoimmunity and cancer and will be accompanied by studies on T-cell specificity towards Coronaviruses and testing of new antiviral mechanisms (patent file in progress). The laboratory of the KG Jebsen Centre is situated at the Department of Immunology, a 350-person department that includes the Blood Bank, several diagnostics sections, 3 Research Centers and about 120 researchers.
The successful applicant will work in an interactive multidisciplinary Centre of scientists, in a strong academic environment, focusing on immune activation and dysregulation, crosstalk between cells, signaling pathways and their outcomes in COVID-19.
The position is a fulltime position and will focus on monitoring vaccine responses in one thousand 3rd or 4th revaccinated high-risk patients that are immunosuppressed due to medical therapy or due to genetic defects. We need to help generate new guidelines for vaccinations for this high-risk group of patients. Existing positive and negative controls and biobanked samples from influenza patients will be compared to vaccinated and COVID-19 cell samples using mass cytometry analysis of phenotype and activation state of immune cells. A clinical trial with transfer of convalescent plasma in COVID-19 patients will be followed for biomarkers of disease severity and treatment success.
- We seek a highly motivated individual holding a PhD degree (or other corresponding education equivalent to a Norwegian doctoral degree) related to molecular biology, cell biology or immunology
- Experience within mass cytometry or advanced flow cytometry cell culture techniques and knowledge of any of the fields of immunity to infections, immunbiology, translational medicine or related fields.
- Candidates who appreciates working in an international and interactive environment.
- The candidate must be fluent in written and spoken English.
- We are looking for highly motivated and structured candidates
- Excellent laboratory skills
- Good collaborative qualities.
It will be an advantage if the applicant can start as soon as possible.
- A challenging and friendly working environment
- Salary NOK 553 500 – 650 300 per annum, depending on qualifications in position as Researcher (position code 1109).
- attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities
How to apply
The application must include:
- Cover letter (how the applicant would fit the call, statement of motivation, summarizing scientific work and research interests )
- CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
- Copies of educational certificates, PhD-certificates (academic transcripts only)
- Letters of recommendation
- A complete list of publications with brief statements of candidate contributions
- List of 3 references (name, relation to candidate, e-mail and phone number)
The application with attachments must be delivered in our electronic recruiting system, Jobbnorge. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.
In assessing the applications, special emphasis will be placed on the documented academic qualifications, the project description (whenever this is required in the call for applicants), and the quality of the project as well as the candidates motivation and personal suitability. Interviews with the best qualified candidates will be arranged
According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.
Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. We also want to have employees with diverse expertise, combinations of subjects, life experience and perspectives. We will make adjustments for employees who require this.
If there are qualified applicants with special needs, gaps in their CVs or immigrant backgrounds, we will invite at least one applicant in each of these groups to an interview.
- Centre Director Professor Ludvig A. Munthe, e-mail: [email protected]
- Senior Adviser HR Heidi Falch Ecklund (questions regarding the online application form), e-mail: [email protected]