Ledig stilling på Universitetet i Oslo

Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Researcher in Cellular Electron Microscopy

Deadline: 31.01.2022

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

The Institute of Clinical Medicine (Klinmed) is one of three institutes under the Faculty. Klinmed is responsible for the Faculty's educational and research activities at Oslo University Hospital and Akershus University Hospital. With about 800 employees spread over approximately 425 man-labour years, Klinmed is the university's largest institute. Our activities follow the clinical activity at the hospitals and are spread across a number of geographical areas.

Job description

A 2-years Researcher position (position code 1109) is available in the Cellular Membrane Dynamics group led by Harald Stenmark at Centre for Cancer Cell Reprogramming (CanCell), Institute of Clinical Medicine. The group has laboratories in Institute for Cancer Research, Oslo University Hospital.

The organization and research focus

The position is financed by a project funded by the European Research Council (ERC), entitled “Coincidence detection of proteins and lipids in regulation of cellular membrane dynamics (CODE)”. The aim of this project is to investigate coincidence detection of proteins and lipids as a mechanism of specific protein recruitment to cellular membranes.

Harald Stenmark is in charge of the CODE project. Stenmark is also director of CanCell, a Norwegian Centre of Excellence which aims at targeting the “Achilles’ heels” of cancer for cancer cell reprogramming. CODE is included in CanCell’s project portfolio.

More about the position

The researcher project will use advanced electron microscopy to study novel coincidence detectors on endosome membranes.

Cellular samples will be analyzed by various electron microscopic methods, including conventional transmission electron microscopy, electron tomography, cryo-electron microscopy and correlative light and electron microscopy.

Qualification requirements

  • Degree equivalent to a Norwegian doctoral degree in molecular biology or cell biology
  • Extensive experience in cell biology, electron microscopy and light microscopy
  • Experience with cell culture work and preparation of cell samples for microscopy, including transfection, preparation of stable cell lines and labeling experiments
  • Extensive experience in sample preparation for electron microscopy, conventional as well as cryo-preparation.
  • Experience with electron tomography, STEM-tomography, tomography reconstruction and modelling
  • Experience with correlative light and electron microscopy (CLEM)
  • Experience with cryo-electron microscopy for structural analyses

Personal skills

The candidate should be highly motivated and dedicated, and should have strong collaboration skills.

We offer

  • A dynamic and stimulating scientific environment in a young, enthusiastic and motivated team of biologists. The Institute for Cancer Research is at the international forefront and houses top modern and excellent lab facilities with a wide range of core facilities (animal, light and electron microscopy, flow cytometry, genomics and bioinformatics, MR), with additional core facilities (mass spec etc) at the Rikshospitalet and UiO sites.
  • Salary NOK 553 500 - NOK 650 300 per annum depending on qualifications in position as Researcher (position code 1109).
  • Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities.

How to apply

The application must include

  • Cover letter (statement of motivation, summarizing scientific work and research interest)
  • CV (summarizing education, positions, pedagogical experience, and other qualifying activity)
  • A complete list of publications
  • Transcripts of university diplomas
  • List of 2 referee persons (name, relation to candidate, e-mail and phone number)

The application with attachments must be delivered in our electronic recruiting system, please follow the link “Apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

In assessing the applications, special emphasis will be placed on the documented academic qualifications, as well as the candidate’s motivation and personal suitability. Interviews with the best qualified candidates will be arranged.

Formal regulations

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. We also want to have employees with diverse expertise, combinations of subjects, life experience and perspectives. We will make adjustments for employees who require this.

If there are qualified applicants with special needs, gaps in their CVs or immigrant backgrounds, we will invite at least one applicant in each of these groups to an interview.

Contact information

Information about the project can be addressed to professor Harald Stenmark, email: [email protected]

Information about the electronic application form can be addressed to senior HR Adviser Thoril Kristiansen, email: [email protected]

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