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Researcher in Molecular and Cell Biology of cancer

Deadline: 25.10.2024

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest rated institution of research and education with 28 000 students and 7000 employees. Its broad range of academic disciplines and internationally esteemed research communities make UiO an important contributor to society.

Department of Biosciences (IBV) is one of nine departments at the Faculty of Mathematics and Natural Sciences. Research in the department is organised in five sections covering topics within biochemistry, molecular biology, physiology, cell biology, genetics, aquatic biology, toxicology, ecology, and evolutionary biology. The Department also operates Finse research station, the Biological research station in Drøbak and UiO's research vessel. Education across these topics is offered for around 300 bachelor, 170 master, and 75 PhD students. With 48 permanent professors/associate professors, post-docs, researchers, technical, and administrative personnel, the Department has a total staff of 260 from more than 30 different countries. The Department aims to maintain high international standards within both research and teaching. The new bachelor program in bioscience is the first of its kind to include programming and computational modelling as core elements.

About the position

Position as Researcher in molecular and cell biology of cancer is available at the Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo. 

The fellowship will be for a period of 2 years. Starting date: as soon as possible.

Job description/project description:

The position is in the group of Prof. Fahri Saatcioglu . The research project is entitled “Molecular and cell biological characterization of the unfolded protein response (UPR) in prostate cancer”. The selected candidate will be part of a major effort in the laboratory to establish the molecular framework as to how major stress signaling functions in an integrated fashion in normal and cancer cells. The work involves genome wide screens to determine molecular interactions within the UPR as well as crosstalk with other signaling pathways. Identified interactions and nodes of importance will be functionally characterized through various approaches in vitro and in vivo. Recent representative papers: Sheng et al., Nature Comm. 2019Pallmann et al., Oncogene, 2019Pallmann et al., Cancer Res. 2021.

The research tasks will require methods within the fields of biochemistry, molecular and cell biology, and genetics, including state of the art CRISPR/Cas9 methods and experiments in mice as a model system.

Qualification requirements:

The Faculty of Mathematics and Natural Sciences has a strategic ambition to be among Europe's leading communities for research, education and innovation. Candidates for these fellowships will be selected in accordance with this, and expected to be in the upper segment of their class with respect to academic credentials.

  • Applicants must hold a degree equivalent to a Norwegian doctoral degree in molecular or cell biology, or a related field, and at least 3 years of postdoctoral research experience
  • Hands-on experience with DNA, mammalian cell culture
  • Practical experience with broad range of molecular and cell biology methods
  • Previous experience with gene targeting (CRISPR/Cas9) and work with mouse as a model system
  • Fluent oral and written communication skills in English

The following is considered an advantage:

  • Knowledge or experience in cell signaling
  • Competence in extracellular vesicle isolation and characterization
  • Competence in immunohistochemistry

Personal skills:

  • A genuine and strong interest in science
  • Strong dedication and ability to work independently as well as lead others
  • Keen interest in solving biological problems
  • Good interpersonal and collaborative skills
  • Ability to design, plan, perform and interpret the results of original experiments 
  • High work ethics

We offer:

  • Salary NOK minimum 575 400 – 700 000 per annum depending on qualifications in position as Researcher (position code 1109)
  • Attractive welfare benefits and a generous pension agreement
  • Professionally stimulating working environment
  • Vibrant international academic environment
  • Oslo’s family-friendly surroundings with their rich opportunities for culture and outdoor activities

The application must include:

  • Cover letter - statement of motivation and research interests
  • CV (summarizing education, laboratory skills, positions and academic work, scientific publications)
  • Copies of educational certificates, academic transcript of records
  • A complete list of publications and up to 5 academic works that the applicant wishes to be considered by the evaluation committee
  • Names and contact details of 3 references (name, relation to candidate, e-mail and telephone number)

The application with attachments must be delivered in our electronic recruiting system, please follow the link “Apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

In assessing the applications, special emphasis will be placed on the documented, academic qualifications, as well as the candidates motivation and personal suitability. Interviews with the best qualified candidates will be arranged.

It is expected that the successful candidate will be able to complete the project in the course of the period of employment.

Formal regulations:

According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results a.o.

The University of Oslo aims to achieve a balanced gender composition in the workforce and to recruit people with ethnic minority backgrounds.

Contact persons:

For further information about the position please contact: 

  • Prof. Fahri Saatcioglu, phone: +47-22854569, e-mail: fahris@uio.no

For technical questions regarding the recruitment system please contact: HR-adviser Nina Holtan, phone: +47 22854424, e-mail: nina.holtan@mn.uio.no

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