Ledig stilling på Universitetet i Oslo

Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Head / Principal Engineer in CRISPR gene therapy group

Deadline: 06.12.2021

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.


Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Job description

The aim of the Haapaniemi group is to build a gene editing platform that can be used to correct patient-specific mutations in ex vivo cell therapies for genetic immune and other rare childhood diseases. We use high-throughput biology techniques to optimize, develop and understand the CRISPR-Cas9 system that forms the base of the platform, and develop and implement methods to evaluate its safety in a clinical setting. We will use the gene editing technologies for the benefit of the patients in the Nordic hospitals.

We announce a 2-year extendable head/principal engineer position and are looking for a motivated, experienced scientist to optimize and conduct routine experimental protocols related to clinical CRISPR translation. Previous experience with primary cell culture and transfection, flow cytometry, or Next Generation Sequencing library preparation is an advantage. You should be comfortable in assisting mouse experiments.

Qualifications

  • MSc or PhD degree in biochemistry, biology or related field.
  • Practical experience with primary human immune cell culture including cell isolation, maintenance, expansion, cryopreservation and transfection.
  • Practical experience with flow cytometry.
  • Practical experience with Next Generation Sequencing library preparation and design.
  • Ability to deliver detailed documentation and structured presentations of experimental results.
  • The successful candidate is enthusiastic, hard-working, well-organized, accurate in their work and can work both independently and in a team.

We offer

  • Salary NOK 468 300 - 563 900 per annum depending on qualifications in a position as a head engineer, position code 1087 or a principal engineer, position code 1085.
  • Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities.

How to apply

The application must include:

  • Cover letter and CV
  • Copies of educational certificates (academic transcripts only)
  • 2-3 reference persons (name, relation to the candidate, e-mail and phone number)

The application with attachments is delivered in our electronic recruiting system, please follow the link “Apply for this job”. Foreign applicants are advised to attach an explanation of their university’s grading system. Please note that all documents should be in English.

When evaluating the application, emphasis will be given to the applicant’s academic and personal prerequisites to carry out the project. Applicants may be called in for an interview.

Formal regulations

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a

balanced gender composition. We also want to have employees with diverse expertise, combinations of subjects, life experience and perspectives. We will make adjustments for employees who require this.

If there are qualified applicants with special needs, gaps in their CVs or immigrant backgrounds, we will invite at least one applicant in each of these groups to an interview.

Contact information

Inquiries about the position can be directed to group leader Emma Haapaniemi, [email protected]

Inquiries about the application can be directed to HR adviser Nina Modahl, [email protected]

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