Ledig stilling på Universitetet i Oslo

Blindern og Urbygningen (Foto: Wikimedia og Colourbox)
Blindern og Urbygningen (Foto: Wikimedia og Colourbox)

Two (2) Postdoctoral Fellowships in Structural Biology and Drug Development

Deadline 28.02.2019

Job description

Universitetet i Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.


Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Flere stillinger fra Universitetet i Oslo

Applications are invited for 3 year positions as Postdoctoral Fellows in the Group of Structural Biology and Drug Development (Luecke group) at the Centre for Molecular Medicine Norway (NCMM), University of Oslo (UiO). We have 2 such positions to fill.

The Group for Structural Biology and Drug Development investigates medically relevant proteins and protein complexes using biophysical, biochemical and structural approaches. The projects aim at understanding structure-function relationships with an emphasis on drug discovery. We employ a variety of biochemical and biophysical techniques (x-ray crystallography, single particle cryo electron microscopy, DSF, ITC, SPR, HDX-MS, SAXS, molecular dynamics simulations etc.). Specific, externally funded projects include inhibitor discovery targeting the Helicobacter pylori pH acclimation system (a pH-gated urea channel and a cytoplasmic urease), and discovery of compounds that reactivate p53 cancer mutants in vitro and in vivo.

The positions are available immediately. We seek highly motivated individuals with an excellent track record and experience in protein purification and biophysical and biochemical characterization of proteins and protein complexes, preferably including membrane proteins. Knowledge of one or more structural biology technique (x-ray crystallography, cryo electron microscopy or NMR) is required. Postdoctoral fellows will be supported in developing their own research area on their path to independence. We offer a stimulating environment with excellent working and social benefits in the Happiest Country on Earth.

More about the position

The appointments are fulltime positions and are made for a period of up to three years. The purpose of the fellowships is to qualify researchers for work in higher academic positions within their disciplines.

Qualification requirements

  • Applicants must hold a degree equivalent to a Norwegian doctoral degree in biochemistry, biophysics, chemistry, or a related area. Doctoral dissertation must be submitted for evaluation by the closing date. Appointment is dependent on the public defence of the doctoral thesis being approved.
  • Hands-on experience with extraction and purification of proteins and assembly of protein complexes (membrane protein experience preferred).
  • Ability to independently perform experiments, analyze and interpret results.
  • Documented ability to write scientific manuscripts (one or more first author papers from Ph.D. and postdoctoral studies will be highly valued).
  • Fluent oral and written communication skills in English.
  • Ability to operate as a team player in a multi-disciplinary environment.

We offer

  • salary NOK 515 200 – 597 400 per annum depending on qualifications in position as Postdoctoral Research Fellow (position code 1352)
  • a professionally stimulating working environment
  • attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities
  • a career development programme designed for researchers at the beginning of their career: https://www.med.uio.no/english/research/postdoctoral-programme/

How to apply

The application must include

  • cover letter (statement of motivation, summarizing scientific work and research interest)
  • CV (summarizing education, positions and other qualifying activity)
  • copies of educational certificates (academic transcripts only)
  • a complete list of publications with brief statement of candidate contribution
  • list of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.

In assessing the applications, special emphasis will be placed on the documented, academic qualifications as well as the candidates motivation and personal suitability. Interviews with the best qualified candidates will be arranged.

Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

No one can be appointed as Postdoctoral Fellow for more than one specified period at the same institution.

According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results etc.

The University of Oslo aims to achieve a balanced gender composition in the workforce and to recruit people with ethnic minority backgrounds.

Contact information

About the positions and the project: Professor Hartmut "Hudel" Luecke, [email protected]

About administrative aspects of the application: HR adviser Ragni Indahl, [email protected]

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