Ledig stilling på Universitetet i Oslo
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PhD Research Fellowship in Structural Biology and Drug Development
Deadline 31.03.2019
Job description
Universitetet i Oslo
The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.
Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.
A 3 year PhD fellowship is available in the Group of Structural Biology and Drug Development (Luecke group) at the Centre for Molecular Medicine Norway (NCMM), University of Oslo (UiO).
The Group for Structural Biology and Drug Development investigates medically relevant proteins and protein complexes using biophysical, biochemical and structural approaches. The projects aim at understanding structure-function relationships with an emphasis on drug discovery. We employ a variety of biochemical and biophysical techniques (x-ray crystallography, single particle cryo electron microscopy, DSF, ITC, SPR, HDX-MS, SAXS, molecular dynamics simulations etc.). Externally funded projects include inhibitor discovery targeting the Helicobacter pylori pH acclimation system (a pH-gated urea channel and a cytoplasmic urease), and discovery of compounds that reactivate p53 cancer mutants in vitro and in vivo. Additional projects are available.
The PhD student will also benefit from career development programs offered both at UiO, the Norwegian BioCat initiative as well as the Nordic EMBL network of the Centre for Molecular Medicine, Norway.
More about the position
A three-year position is available. We seek highly motivated individuals with an excellent track record and experience in protein purification and biophysical and biochemical characterization of proteins and protein complexes. Experience in the field of structural biology techniques is an advantage. We offer stimulating environment with excellent working and social benefits.
The fellowship requires admission to the PhD program at the Faculty of Medicine. The application to the PhD program must be submitted no later than two months after taking up the position.
For more information see:
https://www.med.uio.no/english/research/phd/application/index.html
Qualification requirements
- Applicants must hold a Master’s degree or equivalent in biochemistry, chemistry, molecular biology or a related.
- Hands-on experience with purification of proteins and assembly of protein complexes.
- Ability to independently perform experiments, analyze and interpret the results.
- Excellent interpersonal/communication skills.
- Fluent oral and written communication skills in English.
- Ability to operate as a team player in a multi-disciplinary environment.
We offer
- salary NOK 449 400 – 505 800 per annum depending on qualifications in a position as PhD Research fellow, (position code 1017)
- attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities
How to apply
The application must include
- cover letter statement of motivation and research interests
- CV (summarizing education, positions and academic work)
- copies of educational certificates (academic transcripts only)
- a complete list of publications and academic works, with a brief summary of the candidate’s contribution to each paper
- list of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)
The application with attachments must be delivered in our electronic recruiting system, please follow the link “Apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.
Formal regulations
Please see the guidelines and regulations for appointments to Research Fellowships at the University of Oslo.
According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.
The appointment may be shortened/given a more limited scope within the framework of the applicable guidelines on account of any previous employment in academic positions.
The University of Oslo has an agreement for all employees, aiming to secure rights to research results etc.
Contact information
About the position and the project: Professor Hartmut "Hudel" Luecke, hudel@ncmm.uio.no
About administrative aspects of the application: HR adviser Ragni Indahl, ragni.indahl@ncmm.uio.no
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