Job description

One PhD position in Molecular immunology is available for 3 years with a possibility for a fourth year with 25% compulsory teaching and supervision duties and research assistance at the Institute of Basic Medical Sciences, Department of Molecular Medicine. More information about the institute can be found here: www.med.uio.no/imb/english/

The position is funded by a grant from the Institute of Basal Medical Sciences.

The PhD Candidate will work in the group Molecular Immunology, led by Professor Anne Spurkland. The group is in the fore front of the characterization of the Lck adapter molecule “T cell specific adapter protein” or SH2D2A. The group identified this gene in human activated T cells and has examined the signal transduction pathways which are modulated by this protein in T cells. Recent work of the group focuses on the role of TSAd in T cell activation and in development of disease, in particular cancer and multiple sclerosis. The group has established strong collaborations with scientists from Sweden, UK and the USA.

More about the position

The fellowship period is 3 years and devoted to carrying out a project entitled “TSAd as a target for immunotherapy”. The project will identify novel interaction partners to TSAd in T cells.

The work will involve immunological techniques such as advanced flowcytometry (imaging flowcytometry), Western blotting, immunoprecipitation and molecular biology techniques such as mass spectrometry analysis of complex protein samples, cloning, protein expression, transient expression of plasmids in cell lines and primary cells and mutagenesis of cell lines using CRISPR-Cas9 technology.

The purpose of the fellowship is research training leading to the successful completion of a PhD degree. The fellowship requires admission to the research training program at the Faculty of Medicine. The admission must be approved within three months. For more information see:

http://www.med.uio.no/english/research/doctoral-degree

Qualification requirements

• The applicants must document the following qualifications: either a medical degree (M.D. or equivalent such as cand. med.) or a master’s degree (120 ECTS; minimum grade B ECTS grading scale) or equivalent. The master’s degree must include a thesis of at least 30 ECTS and be in a subject relevant to the position, such as biology, medicine, molecular biology, pharmacology, immunology, physiology chemistry or biochemistry. Ability to work independently as well as in a team.
• Fluent oral and written communication skills in English. For teaching assignments, fluency in a Scandinavian language is mandatory.

The group is interested in hiring an enthusiastic candidate The candidate should preferably have experience with immunological, biochemical or molecular techniques. Skills in flowcytometry, masspectromety or experience with CRISPR-Cas9 technology will be appreciated. Personal qualities relevant for the position will also be taken into account.

In assessing the applications, special emphasis will be placed on the relevance of the candidate’s background.

We offer

• An interesting and challenging assignment
• A productive research environment
• Annual salary of NOK 436 900– 490 900 depending on qualifications, in a position as PhD Research Fellow, (position code 1017)
• Pension and national health insurance is included according to Norwegian law, in addition to several attractive welfare arrangements http://www.uio.no/english/for-employees/employment/welfare
• Welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must include:

• cover letter statement of motivation and research interests
• Application letter including a personal statement explaining the desire to pursue a PhD
• CV that summarizes education, positions and relevant work experience
• Optional: List of publications (please do NOT append the publications)
• Copies of educational certificates and transcript records
• List of 3 references stating relation to the candidate, with contact information.

The application with attachments must be delivered in our electronic recruiting system, please follow the link “Apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

When evaluating the application, emphasis will be given to the applicant’s academic and personal prerequisites to carry out the project. Interviews with selected candidates will be arranged, in person or via Skype. After this initial screening, top ranked candidates for the position will be invited to a second interview with practical tests.

Formal regulations

Please see the guidelines and regulations for appointments to Research Fellowships at the University of Oslo.

According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

The appointment may be shortened/given a more limited scope within the framework of the applicable guidelines on account of any previous employment in academic positions.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results etc.

In accordance with the University of Oslo´s equal opportunities policy, we invite applications from all interested individuals regardless of sex or ethnicity.

Contact information

• Professor Anne Spurkland, Telephone: +47 22851125, email: anne.spurkland@medisin.uio.no

Apply for this job

Søknadsfrist: 01.08.2018

Web: www.uio.no

Kontakt: Professor Anne Spurkland

Telefon: +47 22851125

E-post: anne.spurkland@medisin.uio.no